Various approaches to such protein redesign have drawbacks. Traditional methods include time-consuming trial and error efforts, and many models in the emerging field ...

Binding proteins selectively lock on to metabolites produced by harmful microbes in the gut and prevent them from crossing ...

Google DeepMind announced the launch of AlphaProteo, an AI system to help biological and health researchers design novel, high-strength proteins that bind to target molecules with accuracy and ...

The “ChatGPT moment” for biology proceeds to unfold as protein language models, or machine learning tools trained on large databases of protein sequences, work to decode the language of life with the ...

Scientists have discovered a new way to advance drug discovery and diagnostics by targeting a part of the proteome (the complete set of proteins in an organism) that was previously thought ...

The 2024 Nobel Prize in Chemistry recognized Dr. David Baker for his pioneering work in computational protein design, along with Drs. Demis Hassabis and John Jumper for their contributions to protein ...

Researchers from the Institute for Protein Design and collaborators have designed “minibinders,” or small binding proteins, that may inhibit signaling pathways implicated in autoinflammatory diseases.

Led by Hannes Stärk, a PhD student at MIT and first author, the latest update to the Boltz series of models, BoltzGen, expands the druggable universe by advancing from structure prediction to ...

Cancer has a talent for hiding in plain sight, cloaking itself in sugary molecules that convince the immune system to stand ...

This article is based on a poster originally authored by Peter Hsueh, Lili Qin, Jane Liu and Wenlin Ren. Target proteins are central to the antibody discovery process. These reagents play a critical ...