A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice. The mutation was found to ...

Researchers at UT Southwestern Medical Center have identified a previously unrecognized small protein in cells of the human heart that plays a key role in heart muscle contraction. The protein is made ...

When a muscle contracts, the parts of a sarcomere "shorten" and come closer together. Each cardiac muscle cell can have over 5,000 sarcomeres, which compounds both the shortening and relaxation events ...

Researchers find that deficiency in RPL3L, a ribosome expressed in heart and skeletal muscle, impairs cardiac contractility due to delayed mRNA translation Fukuoka, Japan—A team of researchers have ...

No one can live without a heart pumping blood to the rest of the body. New research from the University of Missouri School of Medicine reveals more information about this vital function and how it’s ...

The PTEN and PI3K-α and -γ are signaling proteins that have important roles in fundamental cellular responses such as proliferation, adhesion, cell size regulation and protection from apoptosis, but ...

Diabetes doesn’t just coexist with heart disease - it actively reshapes the heart’s machinery and the way it makes energy.