When a transplanted organ arrives, it’s like a controlled burn that risks becoming a wildfire. The body’s innate immune system senses damage signals, like heat shock proteins (HSP70), and sounds the ...
Trained immunity provides a unifying framework linking innate immune memory to both protective and maladaptive inflammation ...
Oncolytic viruses trigger immunogenic cell death in tumors, releasing signals that activate innate immune cells and promote tumor-specific T-cell responses. While some oncolytic viruses, including FDA ...
LMU researchers have shown that a particular type of immune cell acts more flexibly than previously thought - with potential for new therapeutic approaches. As part of the innate immune system, ...
The immune system provides constant surveillance for the body, aiming to spot and eliminate disease-causing microbes or ...
A research team led by Jackson Laboratory (JAX) Professor Karolina Palucka, M.D., Ph.D., in collaboration with a research team at Institut Curie in France led by Dr. Nicolas Manel, have addressed a ...
The immune cell repertoire is composed of many different cell types that are orchestrated in response to infection and other pathogens that enter the body. As a result, the body can defend itself ...
The interferon regulatory factor (IRF) family of transcription factors, pivotal for initiating antiviral type I interferon ...
Multicellular organisms are a mosaic of different cells, tissues, and systems, each with their own specific function and interactions with other cells within the organism and/or the larger environment ...
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