Chromatography has long been the workhorse of high-resolution bioseparation. It is the most commonly used technique for preparative work, and is second only to electrophoresis in analysis. Most ...

In recent years many monoclonal antibodies (mAb) have entered the biotherapeutics market, offering new treatments for chronic and life-threatening diseases. Protein A resin captures monoclonal ...

Plasmid DNA (pDNA) is a fundamental starting material for therapeutic development, including for viral vectors, mRNA therapies, and DNA vaccines. Researchers use capture methods such as anion exchange ...

In literature, the terms “ion exchange chromatography” and “ion chromatography” (IC) are often used interchangeably, thanks to the wide use of IEX, and refer to the separation of polar or ionic ...

Fast protein liquid chromatography (FPLC) is, as the term implies, an effective (fast) liquid chromatography technique for the separation of protein molecules. The term also implies that the mobile ...

Nobel Laureate Linus Pauling, Ph.D., predicted in 1939 that hydrogen bonding would prove to be more significant in the field of biology than any other type of chemical bond. His prediction has been ...

Hydrophobic interaction chromatography (HIC) is a powerful technique used for the purification of proteins in analytical and preparatory applications. HIC separates and purifies protein molecules on ...

Ion exchange separates components in a sample depending on their relative ionic strengths and interaction with the stationary phase. The stationary phase is a charged substance that selectively ...

The biopharma industry is looking at continuous chromatography for sensitive molecules. Continuous processes continue to advance in bioprocessing. In downstream processing, continuous chromatography ...