The second component of Virhow's triad is blood coagulation factors (proteins present in plasma). These factors may be roughly divided into two groups: zymogen (proenzymes that can be converted into ...
To determine whether treatment with recombinant human tissue factor pathway inhibitor (TFPI), an inhibitor of the extrinsic coagulation pathway, can improve survival in a clinically relevant model of ...
When injured, endothelial cells permit granulocytes and plasma constituents to enter inflamed tissue, which may lead to organ damage. Endothelial cell inflammation causes vasodilation through the ...
A recent study provides new insights into the mechanisms of coagulation in persons with haemophilia A, the most common form of haemophilia. The research team was able to show that saliva contains ...
The project is led by Professor Wang Guoqing of the School of Basic Medicine and Professor Qiu Jiazhang of the School of Veterinary Medicine of Jilin University. In this study, they performed ...
Blood coagulation protects from microbial infections. A recent study now shows that neutrophils fine tune the procoagulant response to invading pathogens (pages 887–896). Neutrophils degrade an ...
ARCA biopharma Announces AB201 Development Program for Treatment of COVID-19 Associated Coagulopathy
WESTMINSTER, Colo., May 28, 2020 (GLOBE NEWSWIRE) -- ARCA biopharma, Inc. (Nasdaq: ABIO) today announced a new development program to evaluate AB201 (rNAPc2), a potent, selective inhibitor of tissue ...
A novel class of antithrombotic medication, the factor XIa inhibitors, has had a rocky start but is powering through phase III trials, which are now underway. MedPage Today sat down to discuss the ...
Tissue factor (TF), a transmembrane protein overexpressed in tumors such as cervical, head and neck, NSCLC, and pancreatic cancers, initiates the extrinsic coagulation pathway under normal ...
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