A novel class of antithrombotic medication, the factor XIa inhibitors, has had a rocky start but is powering through phase III trials, which are now underway. MedPage Today sat down to discuss the ...

Factor Xa inhibitors are a type of anticoagulant, or blood thinner. They’re a short- and long-term therapy for venous thromboembolism (VTE), which includes deep vein thrombosis (DVT) and pulmonary ...

If you live with atrial fibrillation (sometimes called AF or AFib), a type of irregular heartbeat, you probably take a blood thinner to reduce your risk of stroke and blood clots. Research shows that ...

SOUTH SAN FRANCISCO, Calif., Oct. 28, 2019 /PRNewswire/ -- Portola Pharmaceuticals, Inc. ® (Nasdaq: PTLA) today announced the presentation of a new exploratory analysis of data from ANNEXA-4, the ...

The coagulation cascade is a finely balanced system essential for maintaining haemostasis, yet its disruption can lead to either a propensity for bleeding or an increased risk of clot formation.

Obesity is associated with an increased risk of VTE, and it has been postulated that standard prophylactic LMWH doses may be insufficient to prevent VTE or achieve suggested anti-factor Xa target ...