Improve assay sensitivity and specificity with Locked Nucleic Acid oligonucleotides (LNA oligos) from LGC Biosearch Technologies. LNAs are RNA bases in which the ribose is “locked” with a methylene ...

About nonradioactive nucleic acid detection -- Isolation of DNA from plants -- Isolation of high-molecular-weight DNA from animal cells -- Restriction enzyme digestion, gel electrophoresis and vacuum ...

Fluorescent probes have emerged as indispensable tools in the detection and imaging of nucleic acids, underscoring advances in both fundamental research and clinical diagnostics. By conjugating ...

A team of researchers have developed an easy-to-use colorimetric assay for the detection of food contaminated with salmonella. The assay is based on a novel nucleic acid probe that is cleaved by an ...

Ribonucleic acid binding fluorescent probes have been powerful and important analytical tools for the study of RNA structures and functions. Researchers report a new RNA probe that binds to ...

A plethora of chemical or enzymatic methods are available to generate nucleic acids such as those labeled with fluorophores, enzymes and radioactive phosphates, or nucleotides modified with ...

pt. I. Design of energy transfer probes. Selection of fluorophore and quencher pairs for fluorescent nucleic acid hybridization probes / Salvatore A.E. Marras -- Choosing reporter-quencher pairs for ...

This study is led by Prof. Ying Zhu (Shanghai University), Prof. Zijian Guo (Nanjing University) and Prof. Chunhai Fan (Shanghai Jiao Tong University). They developed a shape-dependent framework ...