Understanding the role of linear ubiquitination in T-tubule biogenesis

Transverse tubules (T-tubules) play a significant role in muscle contraction. However, the underlying mechanism of their ...
Business Wire

OpenFold Biotech AI Research Consortium releases SoloSeq and Multimer, an integrated protein Large Language Model with 3D structure generation

DAVIS, Calif.--(BUSINESS WIRE)--OpenFold, a non-profit artificial intelligence (AI) research consortium, today announced the release of two new tools: 1) SoloSeq, which integrates a new protein Large ...
GEN

Giving Structure to Language: Profluent’s AI Models Move toward Precise and Steerable Protein Design

The “ChatGPT moment” for biology proceeds to unfold as protein language models, or machine learning tools trained on large databases of protein sequences, work to decode the language of life with the ...
The University of Chicago Chronicle

UChicago alum John Jumper shares Nobel Prize for model to predict protein structures

University of Chicago alum John Jumper was awarded a share of the 2024 Nobel Prize in Chemistry on Oct. 9 for developing an AI model that predicts the complex folded structures of proteins. The Royal ...
Phys.org

New AI tool models protein dynamics, aiding drug discovery and protein research

A major scientific advance in protein modeling developed by Microsoft Research AI for Science, has been published in Science. The study introduces BioEmu, a generative deep learning system that ...
GEN

Protein Language Model Hits Undruggable Targets, No Structure Required

Pranam Chatterjee, PhD, assistant professor of bioengineering at the University of Pennsylvania (UPenn), emphasizes that text is all you need for artificial intelligence (AI) models to effectively ...
Morningstar

OpenFold Consortium Releases Preview of OpenFold3: An Open-Source Foundation Model for Structure Prediction of Proteins, Nucleic Acids, and Drugs

Fully open source model accurately predicts the 3D structures of proteins and biomolecules in silico, and serves as a foundational model for next generation of cutting-edge Protein AI tools The ...
Science Daily

Simulating protein structures involved in memory formation

Complex protein interactions at synapses are essential for memory formation in our brains, but the mechanisms behind these processes remain poorly understood. Now, researchers have developed a ...
Wired

Google DeepMind’s Groundbreaking AI for Protein Structure Can Now Model DNA

Google spent much of the past year hustling to build its Gemini chatbot to counter ChatGPT, pitching it as a multifunctional AI assistant that can help with work tasks or the digital chores of ...