The cavity holds a pocket where the small molecule binds. The subunits, being modular, are easily disassembled. In this way, the small-molecule-binding proteins can be treated like Lego blocks and be ...
Jia’s team developed a protocol to improve the screening of protein pockets. This involved identifying the pockets, removing ...
NEW YORK, NY, UNITED STATES, December 3, 2025 /EINPresswire.com/ -- Syntekabio (KOSDAQ: 226330), a global leader in AI-powered drug discovery, is pleased to announce ...
Protein design is crucial for the treatment of human diseases, but traditional protein design methods have some limitations. Site-directed mutagenesis is highly dependent on the physiological ...
The ability to alter proteins to refine control over binding affinity and specificity can create tailored therapeutics with reduced side effects, highly sensitive diagnostic tools, efficient ...
Researchers from the Institute for Protein Design and collaborators have designed “minibinders,” or small binding proteins, that may inhibit signaling pathways implicated in autoinflammatory diseases.
Various approaches to such protein redesign have drawbacks. Traditional methods include time-consuming trial and error efforts, and many models in the emerging field ...
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