The molecular identity of the human mitochondrial calcium uniporter has now been elucidated using integrative genomics. The mammalian uniporter is a protein complex consisting of the inner ...

This mitochondrial process supports the brain cells essential to learning, memory and social recognition. We know that mitochondria are the powerhouses of the cell, but what role do they play in ...

While calcium's importance for our bones and teeth is well known, its role in neurons -- in particular, its effects on processes such as learning and memory -- has been less well defined. A new study ...

Mitochondria are key integrators of cellular calcium (Ca2+) signaling and energy metabolism. Early studies demonstrated that isolated mitochondria could buffer huge amounts of Ca2+ via a highly ...