Bacillus subtilis has emerged as a pre‐eminent model organism for the study and application of protein expression and secretion, owing to its robust secretory pathways and genetic tractability. Its ...
Autophagy and lysosomal pathways orchestrate unconventional secretion of Parkinson’s disease protein
Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...
Avenue Biosciences technology collects data sets on how specific signal peptides impact specific protein targets.
Bacterial interaction with plants and animals, symbiotic or pathogenic, involves the transfer to host cells and tissues of a range of bacterial proteins whose biochemical activities are key to ...
A single damaged protein inside one brain cell may seem insignificant. Yet new research shows how that small mistake can ...
Enodia Therapeutics, a biotechnology company developing novel small-molecule therapies for targeted protein degradation at ...
Gastric cancer cells can activate KRAS-driven signals, enabling autonomous tumor growth by producing their own WNT proteins. New research reveals how gastric cancer cells exploit WNT signaling for ...
Inside the race to turn one of cell biology’s least understood processes into a new foundation for drug development and ...
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