When two defective gene variants combine, normal protein function can sometimes be restored.
Scientists at Pacific Northwest Research Institute (PNRI) have overturned a long-held belief in genetics: that inheriting two ...
In a groundbreaking study published in the in Proceedings of the National Academy of Sciences (PNAS), scientists at Pacific ...
Scientists found that more than 60% of damaging variant pairs in a metabolic enzyme restored normal activity. The study shows ...
Scientists at Pacific Northwest Research Institute (PNRI) report that pairs of genetic variants previously classified as ...
“We’ve shown that, in many cases, two damaging variants can work together to restore protein function,“ said Aimée Dudley, ...
No gene acts alone: interacting variants and protein partnerships can worsen, mask or even rescue disease risk, demanding ...
Sometimes, in genetics, two wrongs do make a right. A research team has recently shown that two harmful genetic variants, ...
Inflammation has to fight pathogens fast—but it can't get out of control. Researchers at the German Cancer Research Center ...
I hate to break this to you, but every child is a genetic experiment – and nature doesn’t care if things go wrong. Our genomes are awful messes created by conflicting evolutionary forces, and every ...
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