Targeted protein degradation presents a promising strategy to address antimicrobial resistance, focusing on innovative ...

A research team engineered a rigid, nanometer-scale protein module to address the challenge of measuring antibody flexibility ...

An estimated 3 million Americans have an inflammatory bowel disease (IBD) such as Crohn's disease or ulcerative colitis. But ...

The protein called intelectin-2 plays another important role by reinforcing the protective mucus layer that lines the ...

As biological data volume continues to grow, sequence-based AI is poised to become the dominant discovery layer across pharma ...

Funding will accelerate development of first-in-class small-molecule drugs for a condition with no approved targeted ...

The mucosal surfaces that line the body are embedded with defensive molecules that help keep microbes from causing inflammation and infections. Among these molecules are lectins—proteins that ...

Polyamines are small molecules naturally present in all cells and are critical in guiding cellular decisions, whereas an ...

Polyamines are small molecules naturally present in all cells and are critical in guiding cellular decisions, whereas an alteration in the abundance of these metabolites is invariably observed in ...

By extending a naturally rigid bacterial protein by 50% while preserving geometry and stability, the study introduces protein ...

Researchers uncovered how polyamines influence cell fate by altering protein phosphorylation and alternative splicing. The ...