63K views · 915 reactions | CDC estimates that Omicron variant...
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63K views · 915 reactions | CDC estimates that Omicron variant...
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Advances in next generation sequencing enable the detection of variants at exceptionally low frequencies. The accurate detection of low-frequency variants is challenging due in part to errors that are introduced during sample preparation, target enrichment, and sequencing. After tagging individual DNA library molecules with adapters containing unique molecular identifiers (UMIs), bioinformatic filters can be applied to identify and correct errors introduced during the sequencing workflow. In thi
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